๐Ÿ•ท๏ธ Chapter 768 ยท Spider Bites

Nelson Textbook of Pediatrics 22nd Edition | Black widow (Latrodectus): ฮฑ-latrotoxin โ†’ massive neurotransmitter release โ†’ severe muscle spasms (abdomen/back), hypertension, tachycardia. Treatment: opioids + benzodiazepines; antivenom (equine) for severe refractory or pregnancy. Brown recluse (Loxosceles): sphingomyelinase D โ†’ dermonecrosis, hemolysis. "Red, white, and blue" sign. No proven therapy โ€“ wound care, pain control. Monitor for systemic loxoscelism.

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๐Ÿ“‹ 30 Clinical Scenarios โ€” Spider Bites

๐Ÿ“‡ Highโ€‘Yield Review Cards

๐Ÿฉบ Clinical Recognition: Spider Envenomation

Select a spider bite presentation to review diagnosis and management (Nelson Ch 768).

๐Ÿ“‹ Stepwise Management of Spider Bites

๐Ÿ”‘ Key Principles โ€” Chapter 768
โ€ข Black widow (Latrodectus): Neurotoxic venom โ†’ latrodectism. Severe muscle spasms (abdomen, back, chest), hypertension, tachycardia, diaphoresis. First-line: opioids (morphine) + benzodiazepines (diazepam). Antivenom (equine) for severe refractory pain, pregnancy, severe hypertension.
โ€ข Brown recluse (Loxosceles): Cytotoxic venom โ†’ dermonecrosis, hemolysis. "Red, white, and blue" sign (violaceous center, pale ischemia, erythema). No proven therapy. Wound care, pain control, tetanus. Dapsone/steroids/hyperbaric oxygen NOT recommended. Systemic loxoscelism (hemolysis, renal failure) โ†’ supportive care.
โ€ข Widow antivenom dose: 1 vial IV (equine). Risk of anaphylaxis. Reserve for severe cases.

    โšก Reflex Prompts โ€” Spider Bite Emergencies

    ๐Ÿ“– Summary: Spider Bites (Nelson 768)