🧬 Autosomal Dominant Hyper‑IgE Syndrome (Job Syndrome)

Nelson Textbook of Pediatrics 22nd Edition — Chapter 165.4 (Inborn Errors with Strong Atopic Diathesis) | STAT3 loss-of-function (dominant negative), cold staphylococcal abscesses, pneumatoceles, coarse facies, hyperextensibility, retained primary teeth, osteopenia, elevated IgE, absent Th17 cells

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📋 30 High‑Yield Clinical Scenarios — AD Hyper‑IgE Syndrome (FCPS Standard)

📇 High‑Yield Review Cards — STAT3 LOF Hyper‑IgE Syndrome

🩺 Symptom‑Based Approach: Recognizing Job Syndrome

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🔄 Stepwise Diagnostic & Management Algorithm for AD Hyper‑IgE Syndrome

    ⚡ Clinical Reflex Prompts — STAT3 Hyper‑IgE Syndrome

    📖 Concise Summary: Autosomal Dominant Hyper‑IgE Syndrome (Job Syndrome)