Nelson Textbook of Pediatrics 22nd Edition | Adenoviruses are non-enveloped DNA viruses causing a wide spectrum of disease: respiratory (pharyngitis, pneumonia), ocular (epidemic keratoconjunctivitis, pharyngoconjunctival fever), gastrointestinal (gastroenteritis, serotypes 40/41), and genitourinary (hemorrhagic cystitis). Over 100 types in 7 species (A-G). Severe disease in immunocompromised (HSCT, SOT). Treatment: supportive; cidofovir for severe cases.
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