Nelson Textbook of Pediatrics 22nd Edition | Respiratory diphtheria (pseudomembrane, bull neck), cutaneous diphtheria, toxin-mediated cardiomyopathy, neuropathy, diphtheria antitoxin (equine), erythromycin/penicillin, vaccination (DTaP, Tdap, Td), prevention (post-exposure prophylaxis).
🌐 paeds.online — Pakistan's Pediatric Platform| Site/Severity | Dose (units) | Notes |
|---|---|---|
| Pharyngeal/laryngeal (early, mild) | 20,000-40,000 U | Administer IV after skin testing for horse serum sensitivity. Obtain from CDC (770-488-7100). |
| Nasopharyngeal | 40,000-60,000 U | |
| Extensive (>48h, bull neck) | 80,000-100,000 U | |
| Cutaneous | 20,000-40,000 U (some use) |