Nelson Textbook of Pediatrics 22nd Edition | HSV-1 and HSV-2. Clinical: gingivostomatitis, herpes labialis, genital herpes, neonatal herpes (SEM, CNS, disseminated), herpes encephalitis, herpetic whitlow, keratitis. Diagnosis: PCR (CSF, blood), viral culture. Treatment: acyclovir (IV for severe/neonatal/CNS, oral for mucocutaneous), valacyclovir. Suppressive therapy for frequent recurrences.
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