Nelson Textbook of Pediatrics 22nd Edition | Vocal nodules (most common cause of chronic hoarseness), recurrent respiratory papillomatosis (HPV 6/11, most common respiratory neoplasm in children), subglottic hemangioma (propranolol), vascular malformations, bronchial carcinoid (most common malignant tumor), mucoepidermoid carcinoma, inflammatory pseudotumor. Clinical: hoarseness, stridor, wheezing, cough, hemoptysis. Diagnosis: laryngoscopy/bronchoscopy, CT/MRI. Treatment: voice therapy, surgical excision, propranolol, cidofovir, HPV vaccine for prevention.
🌐 paeds.online — Pakistan's Pediatric Platform| Neoplasm | Key Features | First-line Treatment |
|---|---|---|
| Vocal nodules | Bilateral, mid-portion of vocal cords, chronic vocal abuse | Voice therapy (primary), antireflux therapy, surgery rarely |
| RRP (HPV 6/11) | Most common respiratory neoplasm in children, recurrent, larynx > trachea | Endoscopic surgical debulking (microdebrider/laser), adjunctive cidofovir, HPV vaccine prevention |
| Subglottic hemangioma | Biphasic stridor, cutaneous hemangioma beard distribution, presents <6 months | Propranolol (first-line), steroids, laser, tracheostomy if severe |
| Bronchial carcinoid | Most common primary malignant tracheobronchial tumor in children, may metastasize | Surgical resection (bronchoscopic or lobectomy) |
| Inflammatory pseudotumor | Benign, locally invasive, post-inflammatory | Surgical excision |