Nelson Textbook of Pediatrics 22nd Edition | Etiology: cystic fibrosis (most common in children), Samter triad (aspirin sensitivity, asthma, polyps), primary ciliary dyskinesia, allergic fungal rhinosinusitis. Antrochoanal polyps (unilateral, from maxillary sinus). Clinical: nasal obstruction, rhinorrhea, hyposmia. Management: intranasal steroids, functional endoscopic sinus surgery, dupilumab for adults.
🌐 paeds.online — Pakistan's Pediatric Platform| Condition | Key Features | Treatment |
|---|---|---|
| Cystic fibrosis-associated polyps | Young child (<12 y), bilateral, recurrent, CF symptoms | Medical: intranasal steroids, dornase alfa; Surgery: FESS if obstructive |
| Antrochoanal polyp | Unilateral, from maxillary sinus, can prolapse into nasopharynx | Surgical excision (endoscopic) |
| Samter triad (ASA triad) | Nasal polyps, asthma, aspirin/NSAID sensitivity; rare in children | Aspirin desensitization (adults), leukotriene modifiers, dupilumab |
| Allergic fungal rhinosinusitis | Nasal polyps, allergic mucin, eosinophilia, fungal hyphae | Surgery, systemic and topical steroids, antifungals |