Nelson Textbook of Pediatrics 22nd Edition | Childhood arterial ischemic stroke (AIS). Etiologies: arteriopathy (focal cerebral arteriopathy, dissection, moyamoya), cardioembolic, prothrombotic states, sickle cell disease. Diagnosis: MRI with DWI (restriction), MRA. Acute management: supportive care (normotension, normoglycemia, normothermia), antithrombotic therapy (aspirin 2-5 mg/kg/day, heparin). Thrombolysis (tPA) not FDA-approved for children. Secondary prevention based on etiology.
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