Nelson Textbook of Pediatrics 22nd Edition | Catecholamine-secreting tumor (adrenal medulla or extra-adrenal paraganglioma). Hypertension (paroxysmal or sustained), headache, sweating, palpitations. Diagnosis: plasma metanephrines. Associated with MEN2, VHL, NF1, SDHx mutations. Treatment: alpha-blockade (phenoxybenzamine) then surgical resection.
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