Select emesis appearance (bright red, coffee‑ground), associated retching, epigastric pain, dysphagia, hepatic signs, and medications → differentiate Mallory‑Weiss tear, peptic ulcer/gastritis, esophagitis, esophageal varices, or vascular malformation.
⚠️ Red flags: massive hematemesis, hemodynamic instability, melena, known liver disease → urgent endoscopy, IV PPI, octreotide/vasopressin, blood transfusion.
Select emesis color (bright red vs coffee‑ground), forceful retching history, epigastric pain, dysphagia, splenomegaly, NSAID use, and endoscopic clues → differential includes Mallory‑Weiss tear, peptic ulcer disease, gastritis, esophagitis, esophageal varices, or Dieulafoy lesion.